Description

(S)-1-(Pyrimidin-2-yl)ethan-1-amine hydrochloride is a high-purity chiral amine building block, specifically the hydrochloride salt of the (S)-enantiomer. This compound is of significant value in pharmaceutical research and development, serving as a critical intermediate for the synthesis of active pharmaceutical ingredients (APIs) and other biologically active molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate a stereochemically defined pyrimidine-containing moiety into their target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the construction of complex molecules where the (S)-configured amine is essential for biological activity.
• Agrochemical Research: Serves as a building block for the synthesis of new pesticides and herbicides with specific stereochemical requirements.
• Ligand and Catalyst Preparation: Can be utilized to create chiral ligands for asymmetric catalysis or metal complexes.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and tool compounds for studying biological systems.
• Academic Research: Used in university and institutional labs for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(S)-1-(Pyrimidin-2-yl)ethan-1-amine hydrochloride
CAS No.	2095456-37-2
Molecular Formula	C6H10ClN3
Molecular Weight	159.62 g/mol
Synonyms	(S)-1-(Pyrimidin-2-yl)ethylamine hydrochloride; (S)-α-Methyl-2-pyrimidinemethanamine hydrochloride; (S)-2-(1-Aminoethyl)pyrimidine hydrochloride; (S)-1-(2-Pyrimidinyl)ethylamine hydrochloride; (S)-(-)-1-(Pyrimidin-2-yl)ethylamine HCl; (S)-Pyrimidin-2-ylethylamine hydrochloride; (S)-Aminoethylpyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(Pyrimidin-2-yl)ethan-1-amine hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.