Description

2-Thia-6-Azaspiro[3.4]Octane 2,2-Dioxide Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic sulfonamide scaffold. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve drug-like properties such as metabolic stability and solubility.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degradation therapeutics.
• Chemical Biology Probes: Utilized in the creation of tool compounds for investigating biological mechanisms and target validation.
• Library Synthesis for High-Throughput Screening: Employed to generate diverse compound libraries for biological activity screening.

Basic Information

Product Name	2-Thia-6-Azaspiro[3.4]Octane 2,2-Dioxide Hydrochloride
CAS No.	2095411-01-9
Molecular Formula	C6H11ClN2O2S
Molecular Weight	210.68 g/mol
Synonyms	2-Thia-6-azaspiro[3.4]octane 2,2-dioxide hydrochloride; 6-Aza-2-thiaspiro[3.4]octane 2,2-dioxide hydrochloride; 2-Thia-6-azaspiro[3.4]octane, 2,2-dioxide, hydrochloride; Spiro[3.4]octane-2-thia-6-aza-2,2-dioxide hydrochloride; 2095411-01-9; 2,2-Dioxo-2-thia-6-azaspiro[3.4]octane hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Thia-6-Azaspiro[3.4]Octane 2,2-Dioxide Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.