Description

1-Bromo-2-Chloro-4-Methoxy-3-Nitro-Benzene is a high-purity, multi-substituted aromatic building block of significant importance in advanced organic synthesis. Its unique halogen and nitro substitution pattern makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive halogen sites for further functionalization.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials due to its aromatic core and substituents.
• Dye and Pigment Intermediate: Employed in the synthesis of advanced colorants and pigments where the nitro and methoxy groups influence color properties and stability.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations to create biaryl and other complex structures.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	1-Bromo-2-Chloro-4-Methoxy-3-Nitro-Benzene
CAS No.	2092776-07-1
Molecular Formula	C7H5BrClNO3
Molecular Weight	266.48 g/mol
Synonyms	2-Bromo-1-Chloro-4-Methoxy-5-Nitrobenzene; 3-Nitro-4-Methoxy-2-Chlorobromobenzene; 4-Methoxy-3-nitro-2-chlorobromobenzene; 1-Bromo-2-chloro-4-methoxy-3-nitrobenzene; Benzene, 1-bromo-2-chloro-4-methoxy-3-nitro-; 2-Chloro-1-bromo-4-methoxy-5-nitrobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-4-Methoxy-3-Nitro-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound may be light-sensitive; store away from direct light exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.