Description

1-Bromo-4-Chloro-5-Methoxy-2-Nitro-Benzene is a high-purity, multi-substituted aromatic compound serving as a critical building block in advanced organic synthesis. Its unique halogen and nitro functional groups make it an indispensable intermediate for constructing complex molecular architectures. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting complex heterocycles.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated nitrobenzene core.
• Dye and Pigment Manufacturing: Serves as a foundational intermediate for producing specialized azo dyes and high-performance pigments.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers requiring specific halogenated aromatic units.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination due to the reactive bromo and chloro substituents.
• Chemical Library Development: A valuable scaffold for combinatorial chemistry and high-throughput screening in medicinal chemistry.

Basic Information

Product Name	1-Bromo-4-Chloro-5-Methoxy-2-Nitro-Benzene
CAS No.	2092613-35-7
Molecular Formula	C7H5BrClNO3
Molecular Weight	266.48 g/mol
Synonyms	4-Bromo-1-Chloro-2-Methoxy-5-Nitrobenzene; 2-Nitro-4-Bromo-1-Chloro-5-Methoxybenzene; 1-Chloro-4-Bromo-5-Methoxy-2-Nitrobenzene; 5-Methoxy-2-Nitro-1-Chloro-4-Bromobenzene; Benzene, 1-bromo-4-chloro-5-methoxy-2-nitro-; 1-Bromo-4-chloro-5-methoxy-2-nitrobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Chloro-5-Methoxy-2-Nitro-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.