Description

5-Bromo-2-Chloro-3-Fluoro-Isonicotinic Acid is a high-purity, multi-halogenated pyridine derivative serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities for bioactivity modulation or further synthetic elaboration.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the halogen pattern influences biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials or liquid crystals.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific halogenated isonicotinic acid scaffolds.
• Academic & Industrial R&D: Used in exploratory chemistry to study structure-activity relationships (SAR) and develop new synthetic methodologies.

Basic Information

Product Name	5-Bromo-2-Chloro-3-Fluoro-Isonicotinic Acid
CAS No.	2091873-10-6
Molecular Formula	C6H2BrClFNO2
Molecular Weight	254.44 g/mol
Synonyms	5-Bromo-2-chloro-3-fluoropyridine-4-carboxylic acid; 2-Chloro-5-bromo-3-fluoroisonicotinic acid; 4-Pyridinecarboxylic acid, 5-bromo-2-chloro-3-fluoro-; 5-Bromo-2-chloro-3-fluoro-4-pyridinecarboxylic acid; 3-Fluoro-5-bromo-2-chloroisonicotinic acid; 5-Br-2-Cl-3-F-isonicotinic acid; BCFI Acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-3-Fluoro-Isonicotinic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The compound is light-sensitive (store away from light) and should be handled in accordance with good laboratory practices for chemicals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.