Description

7-Bromo-2-(Difluoromethyl)Quinoline is a high-value, halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both bromine and difluoromethyl substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the difluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Employed in the creation of specialized organic electronic materials and advanced polymers, leveraging the quinoline core for optoelectronic properties.
• Chemical Synthesis: Serves as a versatile scaffold for further functionalization in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex molecular architectures.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for metal catalysis and as a core structure in catalyst systems.

Basic Information

Product Name	7-Bromo-2-(Difluoromethyl)Quinoline
CAS No.	2091775-45-8
Molecular Formula	C₁₁H₆BrF₂N
Molecular Weight	258.07 g/mol
Synonyms	7-Bromo-2-(difluoromethyl)quinoline; 2-(Difluoromethyl)-7-bromoquinoline; Quinoline, 7-bromo-2-(difluoromethyl)-; 2091775-45-8
EINECS	Contact for details

Quality Control

Our 7-Bromo-2-(Difluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider holding under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.