Description

4,6-Dichloro-5-(Difluoromethyl)Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated pyrimidine core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of agrochemicals and antiviral or anticancer therapeutics. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in antiviral and anticancer research pipelines.
• Agrochemical Synthesis: Serves as a precursor for developing new generation fungicides and herbicides with enhanced efficacy.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new heterocyclic chemistry and structure-activity relationships (SAR).
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of target active ingredients.
• Custom Synthesis: Basis for producing tailored derivatives and analogs for specialized client applications.

Basic Information

Product Name	4,6-Dichloro-5-(Difluoromethyl)Pyrimidin-2-Amine
CAS No.	2091217-55-7
Molecular Formula	C5H3Cl2F2N3
Molecular Weight	217.00 g/mol
Synonyms	2-Amino-4,6-dichloro-5-(difluoromethyl)pyrimidine; 5-(Difluoromethyl)-4,6-dichloropyrimidin-2-amine; 4,6-Dichloro-5-(difluoromethyl)-2-pyrimidinamine; 4,6-Dichloro-5-difluoromethylpyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-5-(Difluoromethyl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.