Description

Phenol, 3-Amino-2-Chloro-6-Fluoro- is a halogenated and aminated phenol derivative, serving as a versatile and high-value synthetic intermediate. Its molecular structure, featuring strategically placed amino, chloro, and fluoro substituents, makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced material science sectors for the synthesis of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a core structure for creating advanced organic electronic materials, dyes, and pigments due to its conjugated phenolic system and modifiable functional groups.
• Polymer Modification: Acts as a monomer or additive for engineering plastics and high-performance polymers to impart specific chemical resistance or thermal properties.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Phenol, 3-Amino-2-Chloro-6-Fluoro-
CAS No.	2090777-63-0
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	3-Amino-2-chloro-6-fluorophenol; 2-Chloro-6-fluoro-3-aminophenol; 6-Fluoro-3-amino-2-chlorophenol; 2-Chloro-6-fluorobenzene-1,3-diamine (tautomer); 1-Amino-2-chloro-5-fluoro-3-hydroxybenzene; ACFP (abbreviation); CAS 2090777-63-0
EINECS	Contact for details

Quality Control

Every batch of Phenol, 3-Amino-2-Chloro-6-Fluoro- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.