Description

Trifluoroethanamine Hydrochloride CAS NO 2089671-65-6 is a high-purity, organofluorine building block salt, essential for introducing the trifluoroethylamine moiety into complex molecular architectures. Its primary value lies in enabling the synthesis of advanced pharmaceutical intermediates and agrochemicals with enhanced metabolic stability and bioavailability. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoroethyl group improves compound efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Material Science: Incorporated into polymers, liquid crystals, and electronic materials to modify solubility, thermal stability, and dielectric properties.
• Bioconjugation and Probe Chemistry: Utilized in the synthesis of biochemical probes and labeling reagents for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules under cGMP or research-grade conditions.

Basic Information

Product Name	Trifluoroethanamine Hydrochloride
CAS No.	2089671-65-6
Molecular Formula	C₂H₅ClF₃N
Molecular Weight	135.51 g/mol
Synonyms	2,2,2-Trifluoroethylamine Hydrochloride; 2,2,2-Trifluoroethan-1-amine Hydrochloride; 1-Amino-2,2,2-trifluoroethane Hydrochloride; Trifluoroethylammonium Chloride; α,α,α-Trifluoroethylamine HCl; TFEA·HCl; (Trifluoroethyl)amine Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Trifluoroethanamine Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity requirements for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all shipments. Our quality commitment supports applications from early-stage research to pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Individual unknown ≤0.5%, Total ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.