Description

7-Bromo-8-Fluoroquinazolin-4(3H)-One is a high-value, multi-functional heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and crop protection agents. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and the synthesis of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Building block for developing new herbicides and fungicides with novel modes of action.
• Chemical Biology: Used in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential monomer or precursor for advanced organic electronic materials and ligands for catalysis.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for client-specific projects.

Basic Information

Product Name	7-Bromo-8-Fluoroquinazolin-4(3H)-One
CAS No.	2089650-78-0
Molecular Formula	C8H3BrFN3O
Molecular Weight	256.03 g/mol
Synonyms	7-Bromo-8-fluoro-3,4-dihydroquinazolin-4-one; 7-Bromo-8-fluoro-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 7-bromo-8-fluoro-; 2089650-78-0; 7-Br-8-F-quinazolin-4-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-8-Fluoroquinazolin-4(3H)-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our standard grade meets the rigorous demands of research and development, with specifications tailored to support cGMP-compliant synthesis when required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.