Description

3-(4-((1H-Imidazol-1-Yl)Methyl)Phenyl)-n-(tert-Butyl)Thiophene-2-Sulfonamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its unique molecular architecture, which combines a thiophene sulfonamide core with an imidazole moiety, making it a critical building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapeutics, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the research and development of new drug candidates, especially for kinase inhibitors and other enzyme-targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro to study biological pathways and protein-ligand interactions due to its specific sulfonamide and heterocyclic functional groups.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the bespoke synthesis of complex molecules for client projects.

Basic Information

Product Name	3-(4-((1H-Imidazol-1-Yl)Methyl)Phenyl)-n-(tert-Butyl)Thiophene-2-Sulfonamide
CAS No.	2089650-46-2
Molecular Formula	C19H21N3O2S2
Molecular Weight	387.52 g/mol
Synonyms	N-(tert-Butyl)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]thiophene-2-sulfonamide; 3-[4-(Imidazol-1-ylmethyl)phenyl]-N-(tert-butyl)thiophene-2-sulfonamide; 2089650-46-2; tert-Butyl 3-(4-(imidazol-1-ylmethyl)phenyl)thiophene-2-sulfonamide; Thiophene-2-sulfonamide, N-(1,1-dimethylethyl)-3-[4-[(1H-imidazol-1-yl)methyl]phenyl]-
EINECS	Contact for details

Quality Control

Our production of 3-(4-((1H-Imidazol-1-Yl)Methyl)Phenyl)-n-(tert-Butyl)Thiophene-2-Sulfonamide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.