Description

Piperidine-1-Carboxylic Acid Hydrochloride is a high-purity organic salt derivative of piperidine, serving as a critical building block in advanced chemical synthesis. Its primary value lies in providing a protected, reactive nitrogen center for constructing complex molecular architectures, particularly in pharmaceutical research. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of piperidine-containing drug candidates, including potential central nervous system (CNS) agents, analgesics, and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the piperidine moiety is integral to biological activity.
• Peptidomimetics & PROTACs: Serves as a versatile scaffold for constructing peptide mimics and Proteolysis-Targeting Chimeras (PROTACs) in drug discovery.
• Ligand & Catalyst Preparation: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Chemical Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs producing custom fine chemicals and reference standards.

Basic Information

Product Name	Piperidine-1-Carboxylic Acid Hydrochloride
CAS No.	2089649-59-0
Molecular Formula	C6H12ClNO2
Molecular Weight	165.62 g/mol
Synonyms	1-Carboxypiperidine Hydrochloride; Piperidine-1-carboxylic acid HCl; 1-Piperidinecarboxylic acid hydrochloride; Piperidine-N-carboxylic Acid Hydrochloride; N-Carboxypiperidine Hydrochloride; 1-Piperidinecarboxylic Acid, Hydrochloride (1:1); UNII-Contact for details; NSC-Contact for details
EINECS	Contact for details

Quality Control

Our Piperidine-1-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.