Description

Exo-3-Azabicyclo[3.2.1]Octan-8-Ol Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a complex, rigid bicyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly within the central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Integral in the synthesis route development for potential new chemical entities (NCEs), especially those targeting neurological receptors.
• Asymmetric Synthesis: Utilized in chiral pool synthesis due to its defined stereochemistry, enabling the construction of enantiomerically pure compounds.
• Chemical Biology Probes: Serves as a precursor for developing tool compounds and molecular probes to study biological pathways.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and scale-up activities.

Basic Information

Item	Detail
Product Name	Exo-3-Azabicyclo[3.2.1]Octan-8-Ol Hydrochloride
CAS No.	2089291-70-1
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	8-Hydroxy-3-azabicyclo[3.2.1]octane hydrochloride (exo-); (1R,2R,5S)-8-Hydroxy-3-azabicyclo[3.2.1]octane hydrochloride; 3-Azabicyclo[3.2.1]octan-8-ol, hydrochloride, (1R,2R,5S)-; exo-8-Hydroxy-3-azabicyclo[3.2.1]octane HCl; Tropane-3-ol, hydrochloride (8-hydroxy derivative); Bicyclic amino alcohol hydrochloride
EINECS	Contact for details

Quality Control

Our Exo-3-Azabicyclo[3.2.1]Octan-8-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.