Description

3-Amino-3-Methylcyclobutan-1-One Hydrochloride is a high-purity, functionalized cyclobutane derivative that serves as a critical building block in advanced organic synthesis. Its unique strained-ring structure and bifunctional amino-ketone group make it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with novel modes of action.
• Material Science: Monomer or cross-linking agent for the development of specialty polymers with tailored thermal and mechanical properties.
• Chemical Synthesis: Versatile scaffold for constructing complex, strained-ring systems and heterocycles in academic and industrial research settings.
• Ligand & Catalyst Development: Starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Amino-3-Methylcyclobutan-1-One Hydrochloride
CAS No.	2089255-22-9
Molecular Formula	C6H12ClNO
Molecular Weight	149.62 g/mol
Synonyms	3-Amino-3-methylcyclobutanone hydrochloride; 3-Methyl-3-aminocyclobutanone HCl; 1-Amino-1-methylcyclobutan-3-one hydrochloride; 3-Amino-3-methyl-1-cyclobutanone hydrochloride; AMCB-HCl; 3-Methyl-3-azacyclobutanone hydrochloride; 3-Aminomethylcyclobutanone hydrochloride (common misnomer)
EINECS	Contact for details

Quality Control

Our 3-Amino-3-Methylcyclobutan-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.