Description

2-Chloro-6-Fluoro-1,5-Naphthyridine is a high-purity, heterocyclic aromatic compound serving as a critical building block in advanced organic synthesis. Its value lies in its dual halogenated structure, which provides distinct reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a precursor for the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Scale-Up: Available for contract research organizations (CROs) and chemical development companies requiring reliable, gram-to-kilogram scale material for process optimization and pilot production.

Basic Information

Product Name	2-Chloro-6-Fluoro-1,5-Naphthyridine
CAS No.	2089060-71-7
Molecular Formula	C8H4ClFN2
Molecular Weight	182.58 g/mol
Synonyms	2-Chloro-6-fluoro-1,5-naphthyridine; 1,5-Naphthyridine, 2-chloro-6-fluoro-; 2089060-71-7; 6-Fluoro-2-chloro-1,5-naphthyridine; 2-Chloro-6-fluoro-[1,5]naphthyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Fluoro-1,5-Naphthyridine is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC-MS, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.