Description

8-Bromo-n-(Furan-2-Ylmethyl)-[1,2,4]Triazolo[4,3-C]Pyrimidin-5-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrimidine class of heterocyclic compounds. This molecule is of significant commercial interest for its role as a key building block in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery programs, particularly those targeting kinase inhibition and other biologically relevant pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Kinase Inhibitor Research: Used as a core scaffold or derivatization point in the development of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry: Provides a versatile heterocyclic template for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	8-Bromo-n-(Furan-2-Ylmethyl)-[1,2,4]Triazolo[4,3-C]Pyrimidin-5-Amine
CAS No.	2083619-61-6
Molecular Formula	C11H9BrN6O
Molecular Weight	321.13 g/mol
Synonyms	8-Bromo-N-[(furan-2-yl)methyl]-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine; 2083619-61-6; 8-Bromo-N-(furan-2-ylmethyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine; 5-Amino-8-bromo-N-(2-furanylmethyl)[1,2,4]triazolo[4,3-c]pyrimidine; 8-Bromo-N-(furan-2-ylmethyl)-1,2,4-triazolo[4,3-c]pyrimidin-5-amine; 8-Bromo-N-(2-furylmethyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
EINECS	Contact for details

Quality Control

Our 8-Bromo-n-(Furan-2-Ylmethyl)-[1,2,4]Triazolo[4,3-C]Pyrimidin-5-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.