Description

(R)-1-(5-Bromo-2-Fluorophenyl)Ethan-1-Amine Hydrochloride is a high-purity chiral amine hydrochloride salt, a critical building block in modern pharmaceutical and agrochemical research. Its value lies in its defined stereochemistry and functionalized aromatic ring, which are essential for creating enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and advanced material synthesis industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and pesticides for enhanced efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Chemistry: Employed in route scouting and scale-up studies for the commercial manufacturing of chiral amines.
• Academic Research: A valuable reagent for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	(R)-1-(5-Bromo-2-Fluorophenyl)Ethan-1-Amine Hydrochloride
CAS No.	2074703-39-0
Molecular Formula	C8H10BrClFN
Molecular Weight	254.53 g/mol
Synonyms	(R)-1-(5-Bromo-2-fluorophenyl)ethanamine hydrochloride; (R)-α-Methyl-5-bromo-2-fluoro-benzylamine hydrochloride; (R)-5-Bromo-2-fluoro-α-methylbenzylamine HCl; (1R)-1-(5-Bromo-2-fluorophenyl)ethan-1-amine hydrochloride; (R)-(-)-1-(5-Bromo-2-fluorophenyl)ethylamine hydrochloride; (R)-1-(5-Bromo-2-fluorophenyl)ethylammonium chloride
EINECS	Contact for details

Quality Control

Our (R)-1-(5-Bromo-2-Fluorophenyl)Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.