Description

[(3R,6S)-6-Methylpiperidin-3-Yl]Methanol Hydrochloride is a high-purity chiral piperidine derivative, a critical building block in modern pharmaceutical synthesis. This compound matters because it provides a stereochemically defined scaffold essential for creating active pharmaceutical ingredients (APIs) with high biological specificity and reduced side-effect profiles. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) agents, antiviral drugs, and other small-molecule therapies where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a stereochemically pure starting material or reagent in catalytic asymmetric reactions to introduce the (3R,6S) configuration.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand and Catalyst Development: Potential precursor for the synthesis of chiral ligands, organocatalysts, or metal complexes used in enantioselective transformations.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	[(3R,6S)-6-Methylpiperidin-3-Yl]Methanol Hydrochloride
CAS No.	2068138-08-7
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	(3R,6S)-6-Methyl-3-piperidinemethanol hydrochloride; (3R,6S)-6-Methylpiperidine-3-methanol hydrochloride; (3R-cis)-6-Methyl-3-piperidinemethanol hydrochloride; 6-Methyl-3-piperidinemethanol hydrochloride, (3R,6S)-; (3R,6S)-6-Methyl-3-hydroxymethylpiperidine hydrochloride; (3R,6S)-3-(Hydroxymethyl)-6-methylpiperidine hydrochloride
EINECS	Contact for details

Quality Control

Our [(3R,6S)-6-Methylpiperidin-3-Yl]Methanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.