Description

(4-Bromo-2,5-Difluorophenyl)Methanamine Hydrochloride is a high-purity, halogenated benzylamine hydrochloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic scaffold with multiple reactive handles for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogen-substituted aromatic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and functional polymers.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways due to its amine functionality.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(4-Bromo-2,5-Difluorophenyl)Methanamine Hydrochloride
CAS No.	2059988-69-9
Molecular Formula	C7H7BrClF2N
Molecular Weight	266.49 g/mol
Synonyms	1-(4-Bromo-2,5-difluorophenyl)methanamine hydrochloride; (4-Bromo-2,5-difluorobenzyl)amine hydrochloride; 4-Bromo-2,5-difluorobenzylamine hydrochloride; α-Amino-4-bromo-2,5-difluorotoluene hydrochloride; Benzenemethanamine, 4-bromo-2,5-difluoro-, hydrochloride; 2059988-69-9; 4-Br-2,5-F2-Bn-NH2·HCl
EINECS	Contact for details

Quality Control

Our (4-Bromo-2,5-Difluorophenyl)Methanamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.