Description

(R)-3-Piperidinemethanamine 2Hcl is a high-purity chiral amine building block supplied as its dihydrochloride salt. This compound is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced agrochemicals, where stereochemistry is essential for biological activity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and insecticides to enhance efficacy and reduce environmental impact.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts in asymmetric synthesis, enabling the production of single-enantiomer compounds.
• Peptidomimetics & Bioactive Molecules: Incorporated into the backbone of peptide analogs and other bioactive molecules to improve metabolic stability and binding affinity.
• Chemical Research: A valuable reagent for medicinal chemistry and process chemistry research in academic and industrial laboratories.
• Custom Synthesis: Available for contract manufacturing and custom synthesis projects requiring high-purity chiral amine derivatives.

Basic Information

Product Name	(R)-3-Piperidinemethanamine 2Hcl
CAS No.	2059913-68-5
Molecular Formula	C6H16Cl2N2
Molecular Weight	187.11 g/mol (Free base: 114.19 g/mol)
Synonyms	(R)-3-(Aminomethyl)piperidine dihydrochloride; (R)-3-Piperidinemethylamine 2HCl; (R)-3-Aminomethylpiperidine dihydrochloride; (3R)-3-Piperidinemethanamine dihydrochloride; (R)-(+)-3-(Aminomethyl)piperidine dihydrochloride; (R)-3-Piperidylmethylamine dihydrochloride; (R)-3-Piperidinamine, N-(aminomethyl)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3-Piperidinemethanamine 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.