Description

2-[trans-3-Aminocyclobutyl]Propan-2-Ol Hcl is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclobutyl amine structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of new therapeutic agents, particularly in areas like central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used as a building block for constructing complex molecules with potential biological activity.
• API Synthesis: Serves as a precursor in the multi-step synthesis of target active pharmaceutical ingredients.
• Chemical Biology Probes: Can be utilized in the development of probes for studying biological pathways and target engagement.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule production.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and methodology development.

Basic Information

Product Name	2-[trans-3-Aminocyclobutyl]Propan-2-Ol Hcl
CAS No.	2058249-61-7
Molecular Formula	C7H15NO • HCl
Molecular Weight	165.66 g/mol (Free base); 202.12 g/mol (HCl salt)
Synonyms	trans-2-(3-Aminocyclobutyl)propan-2-ol hydrochloride; 1-(1-Amino-3-hydroxy-3-methylbutyl)cyclopropane hydrochloride; 2-(trans-3-Aminocyclobutyl)-2-propanol HCl; (1r,3r)-3-Aminocyclobutyl-2-propanol hydrochloride; (trans)-3-Amino-1-(2-hydroxy-2-propyl)cyclobutane hydrochloride; 2-[(1r,3r)-3-Aminocyclobutyl]propan-2-ol hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[trans-3-Aminocyclobutyl]Propan-2-Ol Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.