Description

(R)-2-Amino-3-(2-Hydroxyphenyl)Propanoic Acid Hcl CAS NO 2058231-92-6 is a chiral, non-proteinogenic amino acid derivative, specifically the hydrochloride salt of the (R)-enantiomer of 2-amino-3-(2-hydroxyphenyl)propanoic acid. This compound is a high-value building block in advanced organic synthesis, prized for its defined stereochemistry and functional groups. It is primarily utilized by pharmaceutical research and development organizations for the synthesis of novel active pharmaceutical ingredients (APIs), chiral ligands, and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for neurological and metabolic disorders.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a tyrosine-like phenolic moiety with specific stereochemistry into peptide chains.
• Asymmetric Catalysis: Serves as a precursor for the synthesis of chiral catalysts, ligands, and auxiliaries used in enantioselective transformations.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and as a standard in analytical method development for amino acid analysis.
• Agrochemical Development: Potential use as an intermediate in the synthesis of chiral, bioactive compounds for crop protection.
• Material Science: Can be utilized in the development of specialty polymers and functional materials requiring chiral, aromatic amino acid components.

Basic Information

Product Name	(R)-2-Amino-3-(2-Hydroxyphenyl)Propanoic Acid Hydrochloride
CAS No.	2058231-92-6
Molecular Formula	C9H12ClNO3
Molecular Weight	217.65 g/mol
Synonyms	(R)-2-Amino-3-(2-hydroxyphenyl)propanoic acid hydrochloride; (R)-2-Hydroxy-D-phenylalanine hydrochloride; (R)-2-Hydroxy-D-Phe-OH·HCl; (R)-3-(2-Hydroxyphenyl)alanine hydrochloride; D-2-Hydroxyphenylalanine HCl; (R)-β-(2-Hydroxyphenyl)-α-alanine hydrochloride; (2R)-2-Amino-3-(2-hydroxyphenyl)propanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-3-(2-Hydroxyphenyl)Propanoic Acid HCl is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and chiral integrity. We provide full traceability and Certificates of Analysis (COA) detailing specifications such as assay (HPLC), enantiomeric excess (Chiral HPLC), and impurity profiles. Our quality commitment aligns with the standards expected for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition (Sulfated Ash)	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.