Description

(1R,3S)-3-Aminocyclohexanecarboxylic Acid Hydrochloride is a high-purity chiral building block essential for modern pharmaceutical and agrochemical synthesis. Its defined stereochemistry makes it a critical intermediate for developing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for constructing complex molecules in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptide Mimetics & Conformationally Restricted Analogs: Used to introduce constrained cyclohexane scaffolds into peptide backbones to enhance stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in herbicides and fungicides.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis.
• Academic & Industrial Research: A valuable tool for medicinal chemistry programs and method development in organic synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke chemical synthesis projects requiring high stereochemical purity.

Basic Information

Item	Details
Product Name	(1R,3S)-3-Aminocyclohexanecarboxylic Acid Hydrochloride
CAS No.	2058044-04-3
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	(1R,3S)-3-Aminocyclohexane-1-carboxylic acid hydrochloride; (1R,3S)-3-Amino-1-cyclohexanecarboxylic acid HCl; cis-3-Aminocyclohexanecarboxylic acid hydrochloride (specifying (1R,3S)); 3-Aminocyclohexanecarboxylic acid HCl (cis-isomer); Rel-((1R,3S)-3-Aminocyclohexyl)carboxylic acid hydrochloride; 3-ACHC HCl; 3-ACHC hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,3S)-3-Aminocyclohexanecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,3S)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.