Description

[2-[(3R,4S)-4-Ethyl-1-[(Phenylmethoxy)Carbonyl]-3-Pyrrolidinyl]-2-Oxoethyl]Dimethyl-Sulfoxonium Inner Salt is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfoxonium ylide structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in modern medicinal chemistry where precise stereochemistry is paramount. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, especially within the fields of oncology and targeted drug delivery.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for the production of complex, stereochemically-defined active pharmaceutical ingredients.
• Medicinal Chemistry Research: Used in research and development for constructing novel molecular scaffolds in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.
• Sulfoxonium Ylide Chemistry: Utilized in specialized organic transformations, such as metal-carbene transfer reactions, for C-H functionalization and cyclopropanation.
• Asymmetric Synthesis: Leverages its defined (3R,4S) stereochemistry to induce chirality in downstream synthetic targets.

Basic Information

Product Name	[2-[(3R,4S)-4-Ethyl-1-[(Phenylmethoxy)Carbonyl]-3-Pyrrolidinyl]-2-Oxoethyl]Dimethyl-Sulfoxonium Inner Salt
CAS No.	2050038-78-1
Molecular Formula	C18H25NO4S
Molecular Weight	351.46 g/mol
Synonyms	Dimethyl-[2-oxo-2-[(3R,4S)-1-(phenylmethoxycarbonyl)-4-ethyl-3-pyrrolidinyl]ethyl]-sulfoxonium; (3R,4S)-1-(Benzyloxycarbonyl)-4-ethyl-3-(2-oxo-2-(dimethylsulfoxonio)ethyl)pyrrolidinium; Sulfoxonium Ylide Intermediate CBZ-Protected; 1-[(Benzyloxy)carbonyl]-4-ethyl-3-[2-oxo-2-(dimethylsulfoxonio)ethyl]-(3R,4S)-pyrrolidinium; (3R,4S)-1-CBZ-4-Ethyl-3-(2-oxo-2-(dimethylsulfoxonio)ethyl)pyrrolidinium Inner Salt
EINECS	Contact for details

Quality Control

Our [2-[(3R,4S)-4-Ethyl-1-[(Phenylmethoxy)Carbonyl]-3-Pyrrolidinyl]-2-Oxoethyl]Dimethyl-Sulfoxonium Inner Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.