Description

(2-Bromo-4-Chlorophenyl)Methanamine Hydrochloride is a high-purity, halogenated benzylamine hydrochloride salt, a crucial building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive amine handle for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antimicrobial drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral auxiliaries, ligands for metal catalysis, and other specialty reagents.
• Material Science Research: Employed in the synthesis of monomers or functional agents for advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle for bioconjugation or as a scaffold in probe molecule development.
• Custom Synthesis and Scale-up: An essential starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	(2-Bromo-4-Chlorophenyl)Methanamine Hydrochloride
CAS No.	2048273-70-5
Molecular Formula	C7H8BrClN•HCl
Molecular Weight	270.96 g/mol (Free base: 234.51 g/mol)
Synonyms	1-(2-Bromo-4-chlorophenyl)methanamine hydrochloride; (2-Bromo-4-chloro-benzyl)amine hydrochloride; 2-Bromo-4-chlorobenzylamine hydrochloride; α-Amino-2-bromo-4-chlorotoluene hydrochloride; 2-Bromo-4-chloro-α-toluidine hydrochloride; Benzenemethanamine, 2-bromo-4-chloro-, hydrochloride (1:1); 2048273-70-5
EINECS	Contact for details

Quality Control

Our (2-Bromo-4-Chlorophenyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.