Description

Rac-(3Ar,6S,6As)-Octahydrocyclopenta[B]Pyrrol-6-Ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic interest. Its complex, fused bicyclic structure makes it a valuable scaffold for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries seeking to explore new therapeutic modalities, particularly in central nervous system (CNS) and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Asymmetric Synthesis: Employed as a building block in stereoselective synthesis due to its defined stereocenters (3Ar,6S,6As).
• Process Chemistry Development: Utilized in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Fundamental research tool in organic synthesis and methodology development within university and corporate laboratories.

Basic Information

Product Name	Rac-(3Ar,6S,6As)-Octahydrocyclopenta[B]Pyrrol-6-Ol Hydrochloride
CAS No.	2044705-91-9
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	(3aR,6S,6aS)-Octahydrocyclopenta[b]pyrrol-6-ol hydrochloride; (±)-(3aR,6S,6aS)-Octahydro-1H-cyclopenta[b]pyrrol-6-ol hydrochloride; rac-(3aR,6S,6aS)-Octahydrocyclopenta[b]pyrrol-6-ol HCl; Cyclopentapyrrolidine-6-ol hydrochloride (racemic stereoisomer); 6-Hydroxyoctahydrocyclopenta[b]pyrrole hydrochloride
EINECS	Contact for details

Quality Control

Our Rac-(3Ar,6S,6As)-Octahydrocyclopenta[B]Pyrrol-6-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC), and other critical specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.