Description

2-Cyclopropylmorpholine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant commercial interest. Its unique fused bicyclic structure makes it a valuable synthon for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce cyclopropyl and morpholine motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and library synthesis due to its constrained geometry and potential for hydrogen bonding.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides that incorporate nitrogen-containing heterocycles.
• Ligand and Catalyst Development: The morpholine nitrogen can be utilized in the design of chiral ligands or organocatalysts for asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Cyclopropylmorpholine Hydrochloride
CAS No.	2044705-23-7
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	2-Cyclopropylmorpholine HCl; Morpholine, 2-cyclopropyl-, hydrochloride; 2-Cyclopropylmorpholine monohydrochloride; 4-Cyclopropylmorpholin-2-one hydrochloride (tautomer); Cyclopropylmorpholine hydrochloride; CAS 2044705-23-7
EINECS	Contact for details

Quality Control

Our 2-Cyclopropylmorpholine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide detailed Certificates of Analysis (COA) with every shipment to ensure traceability and compliance with your internal specifications and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.