Description

7-(Trifluoromethyl)-2,3-Dihydroquinazolin-4(1H)-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because the trifluoromethyl group imparts unique physicochemical properties, such as enhanced metabolic stability and lipophilicity, which are critical for developing bioactive molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science: Acts as a building block for specialty polymers and advanced organic electronic materials due to its unique electronic properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	7-(Trifluoromethyl)-2,3-Dihydroquinazolin-4(1H)-One
CAS No.	2044704-73-4
Molecular Formula	C9H7F3N2O
Molecular Weight	216.16 g/mol
Synonyms	7-(Trifluoromethyl)-1,2,3,4-tetrahydroquinazolin-4-one; 4(1H)-Quinazolinone, 2,3-dihydro-7-(trifluoromethyl)-; 7-Trifluoromethyl-2,3-dihydro-1H-quinazolin-4-one; 7-Trifluoromethyl-1,2,3,4-tetrahydroquinazolin-4-one; 7-(Trifluoromethyl)-3,4-dihydroquinazolin-4(1H)-one; 7-(Trifluoromethyl)-1,2,3,4-tetrahydro-4-quinazolinone
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-2,3-Dihydroquinazolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.