Description

2-(2,2-Difluorocyclopropyl)Ethan-1-Amine Hydrochloride is a high-purity, specialty organic salt featuring a unique difluorocyclopropyl moiety. This compound serves as a critical pharmaceutical intermediate and advanced building block in modern synthetic chemistry, enabling the introduction of fluorine atoms and strained ring systems into target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used as a building block for developing new-generation pesticides and herbicides with enhanced activity and environmental profile.
• Fluorinated Compound Research: Essential for medicinal chemistry programs exploring the effects of fluorine substitution and strained ring systems on drug-like properties (e.g., metabolic stability, bioavailability).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Advanced Material Precursor: Potential use in creating specialty polymers and functional materials with unique electronic or surface properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects.

Basic Information

Product Name	2-(2,2-Difluorocyclopropyl)Ethan-1-Amine Hydrochloride
CAS No.	2031258-87-2
Molecular Formula	C5H10ClF2N
Molecular Weight	157.59 g/mol
Synonyms	2-(2,2-Difluorocyclopropyl)ethanamine hydrochloride; 2-(2,2-Difluorocyclopropyl)ethylamine hydrochloride; 1-(2,2-Difluorocyclopropyl)methanamine hydrochloride; 2,2-Difluorocyclopropanemethanamine hydrochloride; 2-(2,2-Difluorocyclopropyl)ethan-1-amine HCl; 2031258-87-2; Difluorocyclopropyl ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-(2,2-Difluorocyclopropyl)Ethan-1-Amine Hydrochloride is manufactured under a cGMP-compliant quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are supported by a comprehensive Certificate of Analysis (COA) detailing all critical quality attributes. We adhere to stringent in-process controls and final release specifications, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.