Description

Tos-Peg5-Ch2Co2H CAS NO 2028284-73-1 is a heterobifunctional polyethylene glycol (PEG) derivative featuring a tosyl (Tos) group for nucleophilic substitution and a carboxylic acid (COOH) terminus for conjugation. This compound is engineered to serve as a versatile linker in bioconjugation and pharmaceutical development, enabling the controlled attachment of molecules, peptides, or proteins. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceuticals, advanced drug delivery systems, and diagnostic reagent development.

Application

• As a key heterobifunctional crosslinker for modifying proteins, peptides, and antibodies.
• In the synthesis of PEGylated drug conjugates to enhance solubility, stability, and pharmacokinetic profiles.
• For the functionalization of nanoparticles and liposomes to create targeted drug delivery platforms.
• As a building block in the development of diagnostic assays and biosensors.
• In the preparation of hydrogel precursors and other biomaterials for tissue engineering.
• For surface modification and biocompatibility enhancement of medical devices and implants.

Basic Information

Product Name	Tos-Peg5-Ch2Co2H
CAS No.	2028284-73-1
Molecular Formula	C24H40O11S
Molecular Weight	536.6 g/mol
Synonyms	2-[2-[2-[2-[2-(4-Methylbenzenesulfonyloxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic Acid; Tos-PEG5-acid; α-Tosyl-ω-carboxy pentadecaethylene glycol; PEG5 Tosylate Acetic Acid; 4-Methylbenzenesulfonic acid 2,5,8,11,14-pentaoxahexadecan-16-yl ester; Heterobifunctional PEG, Tosyl-PEG5-COOH; Tosyl-Pentaethylene glycol-Acid
EINECS	Contact for details

Quality Control

Our Tos-Peg5-Ch2Co2H is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.