Description

(1S,2S,3S,5R)-3-(2-Hydroxyethoxy)-5-[7-Methoxy-5-(Propylthio)-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-3-Yl]-1,2-Cyclopentanediol CAS NO 2024557-22-8 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel, targeted therapeutic agents, offering researchers a reliable building block for drug discovery and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating next-generation medications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel adenosine receptor modulators and other purine-based therapeutics.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Research: Employed as a tool compound in pharmacological assays to study specific enzyme or receptor interactions.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex molecular architectures in custom synthesis projects.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	(1S,2S,3S,5R)-3-(2-Hydroxyethoxy)-5-[7-Methoxy-5-(Propylthio)-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-3-Yl]-1,2-Cyclopentanediol
CAS No.	2024557-22-8
Molecular Formula	C16H23N5O5S
Molecular Weight	397.45 g/mol
Synonyms	5-(7-Methoxy-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-3-(2-hydroxyethoxy)cyclopentane-1,2-diol; (1S,2S,3S,5R)-3-(2-Hydroxyethoxy)-5-(7-methoxy-5-propylsulfanyl-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)cyclopentane-1,2-diol; Adenosine derivative intermediate; Triazolopyrimidine cyclopentanediol derivative; AZD-4635 intermediate; AR-Lux intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (1S,2S,3S,5R)-3-(2-Hydroxyethoxy)-5-[7-Methoxy-5-(Propylthio)-3H-1,2,3-Triazolo[4,5-D]Pyrimidin-3-Yl]-1,2-Cyclopentanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure compliance with research-grade and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.