Description

(S)-3-(tert-Butyl)-4-(4',6'-Dimethoxy-[1,1':3',1''-Terphenyl]-5'-Yl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole is a high-value, chiral organophosphorus compound of significant interest in advanced organic synthesis. Its unique structure, featuring a sterically hindered tert-butyl group and an extended terphenyl system, makes it a sophisticated ligand or building block for asymmetric catalysis and materials science. This compound is primarily sought after by research and development teams in the pharmaceutical and specialty chemical industries for creating novel active ingredients and functional materials. CAS No. 2021201-99-8.

Application

• Asymmetric Catalysis: Serves as a chiral ligand or precursor for transition metal catalysts used in enantioselective synthesis of pharmaceuticals and agrochemicals.
• Pharmaceutical Intermediate: A key chiral building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or oncology targets.
• Materials Science Research: Used in the development of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge transport materials, due to its rigid, conjugated structure.
• Chemical Biology Probes: Employed in the design of molecular probes to study enzyme mechanisms or biological pathways involving phosphorus.
• Academic & Industrial R&D: A valuable reagent for methodology development in organic chemistry, exploring new P-C bond forming reactions or stereoselective transformations.

Basic Information

Item	Detail
Product Name	(S)-3-(tert-Butyl)-4-(4',6'-Dimethoxy-[1,1':3',1''-Terphenyl]-5'-Yl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole
CAS No.	2021201-99-8
Molecular Formula	C34H35O3P
Molecular Weight	522.62 g/mol
Synonyms	(S)-3-tert-Butyl-4-(4',6'-dimethoxy-[1,1':3',1''-terphenyl]-5'-yl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; (S)-3-(tert-Butyl)-4-(4',6'-dimethoxy-[1,1':3',1''-terphenyl]-5'-yl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; Chiral Dihydrobenzooxaphosphole Derivative; Terphenyl-Substituted Oxaphosphole; Asymmetric Organophosphorus Ligand; CAS 2021201-99-8
EINECS	Contact for details

Quality Control

Every batch of (S)-3-(tert-Butyl)-4-(4',6'-Dimethoxy-[1,1':3',1''-Terphenyl]-5'-Yl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole is produced and analyzed under strict quality management systems. We provide comprehensive analytical data including chiral purity (enantiomeric excess), chemical purity (HPLC), and structural confirmation (NMR, MS) to ensure it meets the exacting standards for research and process development. A Certificate of Analysis (COA) detailing all specifications is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.