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((1R,8S,9S)-Bicyclo[6.1.0]Non-4-Yn-9-Yl)Methyl 2-Aminoethylcarbamate CAS NO 2008714-39-2
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CAS No.:2008714-39-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
((1R,8S,9S)-Bicyclo[6.1.0]Non-4-Yn-9-Yl)Methyl 2-Aminoethylcarbamate is a high-purity, advanced bifunctional chemical intermediate featuring a strained bicyclic alkyne core and a reactive carbamate-protected amine. This compound is engineered for precision in demanding synthetic applications where controlled reactivity and structural integrity are paramount. It is primarily utilized by research institutions and pharmaceutical developers in the synthesis of novel bioactive molecules, including potential drug candidates and specialized probes for chemical biology.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of complex, strained-ring-containing active pharmaceutical ingredients (APIs) and drug conjugates.
- Bioconjugation & Probe Development: The reactive alkyne moiety enables efficient, site-specific labeling of biomolecules (e.g., proteins, antibodies) via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (SPAAC) click chemistry.
- Chemical Biology Research: Used to create activity-based probes (ABPs) and affinity tags for studying enzyme function, protein-protein interactions, and cellular pathways.
- Materials Science: Serves as a functional monomer or cross-linker precursor for developing advanced polymers with tailored thermal or mechanical properties.
- Agrochemical Synthesis: An intermediate in the research and development of novel crop protection agents with unique modes of action.
- Diagnostic Reagent Manufacturing: Employed in the production of specialized reagents for diagnostic assays and imaging agents.
Basic Information
| Item | Details |
|---|---|
| Product Name | ((1R,8S,9S)-Bicyclo[6.1.0]Non-4-Yn-9-Yl)Methyl 2-Aminoethylcarbamate |
| CAS No. | 2008714-39-2 |
| Molecular Formula | C13H20N2O2 |
| Molecular Weight | 236.31 g/mol |
| Synonyms | (1R,8S,9S)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl (2-aminoethyl)carbamate; BCN-PEG2-Amine; BCN-NH2; (BCN-9-yl)methyl (2-aminoethyl)carbamate; BCN-Amine; BCN Linker Amine; BCN-PEG2-NH2; Bicyclo[6.1.0]non-4-yn-9-ylmethyl 2-aminoethylcarbamate |
| EINECS | Contact for details |
Quality Control
Every batch of ((1R,8S,9S)-Bicyclo[6.1.0]Non-4-Yn-9-Yl)Methyl 2-Aminoethylcarbamate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure compliance with exacting purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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