Description

8-Chloro-1,5-naphthyridine-3-carboxylic acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique fused-ring structure, which provides a versatile scaffold for constructing complex molecules with targeted biological or material properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its naphthyridine core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis or metal-organic frameworks (MOFs).
• Material Science: Incorporated into the design of organic semiconductors, fluorescent dyes, or photoactive materials due to its conjugated aromatic system.
• Chemical Biology: Utilized as a molecular probe or tag in biochemical research to study protein interactions or cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic projects.

Basic Information

Product Name	8-Chloro-1,5-naphthyridine-3-carboxylic acid
CAS No.	2007916-75-6
Molecular Formula	C9H5ClN2O2
Molecular Weight	208.60 g/mol
Synonyms	8-Chloro-1,5-naphthyridine-3-carboxylic acid; 1,5-Naphthyridine-3-carboxylic acid, 8-chloro-; 8-Chloro-1,5-naphthyridine-3-carboxylate; 3-Carboxy-8-chloro-1,5-naphthyridine; 8-Chloro-1,5-naphthyridine-3-carboxylic acid (CAS 2007916-75-6); 8-Chloro-1,5-naphthyridine-3-carboxylic acid, 95+%; 8-Chloro-1,5-naphthyridine-3-carboxylic acid, 98+%
EINECS	Contact for details

Quality Control

Our production of 8-Chloro-1,5-naphthyridine-3-carboxylic acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.