Description

6-Bromo-2-(3-Chloropropyl)Quinazoline is a high-purity, multi-functional organic building block with the CAS number 2006277-97-8. This compound is valued for its versatile reactivity, serving as a key intermediate in the synthesis of complex molecules for advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by academic institutions for material science studies. Its specific halogenated quinazoline structure makes it a critical precursor for targeted modifications in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated quinazoline core.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Synthesis: Employed in organic chemistry laboratories for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to its reactive bromo and chloropropyl groups.
• Bioconjugation & Probe Synthesis: Utilized in the development of biochemical probes and diagnostic agents where the quinazoline scaffold acts as a fluorescent tag or linking moiety.

Basic Information

Item	Details
Product Name	6-Bromo-2-(3-Chloropropyl)Quinazoline
CAS No.	2006277-97-8
Molecular Formula	C₁₁H₁₀BrClN₂
Molecular Weight	285.57 g/mol
Synonyms	6-Bromo-2-(3-chloropropyl)quinazoline; 2-(3-Chloropropyl)-6-bromoquinazoline; Quinazoline, 6-bromo-2-(3-chloropropyl)-; 6-Bromo-2-(3-chloropropyl)-quinazoline; 2006277-97-8; 6-Bromo-2-(3-chloropropyl)quinazoline CAS 2006277-97-8
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(3-Chloropropyl)Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.