Description

2-(3-Chloropropyl)-6-Fluoroquinazoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinazoline core functionalized with chloropropyl and fluoro substituents. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel small-molecule drugs, particularly in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study specific enzyme pathways and biological mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	2-(3-Chloropropyl)-6-Fluoroquinazoline
CAS No.	2006277-67-2
Molecular Formula	C₁₁H₁₀ClFN₂
Molecular Weight	224.66 g/mol
Synonyms	6-Fluoro-2-(3-chloropropyl)quinazoline; 2-(3-Chloropropyl)-6-fluoroquinazoline; Quinazoline, 2-(3-chloropropyl)-6-fluoro-; 2006277-67-2
EINECS	Contact for details

Quality Control

Our 2-(3-Chloropropyl)-6-Fluoroquinazoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.