Description

2-(2-Chloroethyl)-6,7-Dimethoxyquinazoline is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted therapeutic agents, particularly kinase inhibitors and other small molecule drugs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of novel compound libraries.
• Chemical Synthesis: Serves as a versatile scaffold for further functionalization, enabling the exploration of new chemical entities with potential biological activity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in API manufacturing processes.

Basic Information

Product Name	2-(2-Chloroethyl)-6,7-Dimethoxyquinazoline
CAS No.	2006277-21-8
Molecular Formula	C₁₂H₁₃ClN₂O₂
Molecular Weight	252.70 g/mol
Synonyms	6,7-Dimethoxy-2-(2-chloroethyl)quinazoline; 2-(2-Chloroethyl)-6,7-dimethoxyquinazoline; Quinazoline, 2-(2-chloroethyl)-6,7-dimethoxy-; 6,7-Dimethoxy-2-(2-chloroethyl)-1,3-diazanaphthalene
EINECS	Contact for details

Quality Control

Our 2-(2-Chloroethyl)-6,7-Dimethoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.