Description

3-Bromo-4-(Difluoromethoxy)Phenylacetic Acid is a high-purity, synthetically valuable aromatic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and versatile building block in modern organic synthesis. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and pesticides, leveraging the difluoromethoxy and bromo substituents for enhanced bioactivity.
• Ligand and Catalyst Development: Used in organometallic chemistry to create novel ligands for catalysis and material science applications.
• Chemical Research (R&D): Essential for academic and industrial research in medicinal chemistry and process development for scale-up.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other performance chemicals.

Basic Information

Product Name	3-Bromo-4-(Difluoromethoxy)Phenylacetic Acid
CAS No.	2006277-18-3
Molecular Formula	C9H7BrF2O3
Molecular Weight	281.05 g/mol
Synonyms	2-(3-Bromo-4-(difluoromethoxy)phenyl)acetic acid; [3-Bromo-4-(difluoromethoxy)phenyl]acetic acid; 3-Bromo-4-(difluoromethoxy)benzeneacetic acid; α-(3-Bromo-4-(difluoromethoxy)phenyl)acetic acid; BDMPA; CAS 2006277-18-3
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Difluoromethoxy)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.