Description

Tetrakis[n-Tetrachlorophthaloyl-(R)-tert-Leucinato]Dirhodium Bis(Ethyl Acetate) Adduct is a highly specialized, chiral dirhodium(II) carboxylate complex, a critical class of catalysts in modern asymmetric synthesis. Its value lies in enabling highly enantioselective C–H functionalization, cyclopropanation, and other carbene transfer reactions, which are pivotal for constructing complex chiral molecules with high precision. This product is essential for R&D and process chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel, single-enantiomer active ingredients.

Application

• Asymmetric C–H Insertion Reactions: For the enantioselective functionalization of inert C–H bonds, a key step in streamlining synthetic routes to complex molecules.
• Enantioselective Cyclopropanation: As a catalyst for the synthesis of chiral cyclopropane rings, important structural motifs in many bioactive compounds.
• Pharmaceutical Intermediate Synthesis: In the research and development of chiral active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Agrochemical Product Development: For creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Synthesis: In the production of high-value, chiral specialty chemicals and aroma compounds.
• Academic and Industrial R&D: As a benchmark catalyst for methodological development in asymmetric catalysis and organometallic chemistry.

Basic Information

Product Name	Tetrakis[n-Tetrachlorophthaloyl-(R)-tert-Leucinato]Dirhodium Bis(Ethyl Acetate) Adduct
CAS No.	2001054-66-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dirhodium(II) Tetrakis[n-tetrachlorophthaloyl-(R)-tert-leucinate]; Rh2(R-TCPTTL)4; Rh2(S-TCPTTL)4 (enantiomer); Chiral Dirhodium Tetracarboxylate Catalyst; Tetrakis(α-(tetrachlorophthalimido)-tert-leucinato)dirhodium; Dirhodium(II) (R)-Tetrakis(4-tert-butyl-2-oxo-1,3-dioxolane-4-carboxylate) (common structural analog); Asymmetric Dirhodium Catalyst
EINECS	Contact for details

Quality Control

Every batch of our chiral dirhodium catalysts is produced and tested under strict quality protocols to ensure consistent, high-performance catalytic activity and enantioselectivity. We employ advanced analytical techniques, including HPLC, NMR, and elemental analysis, to verify chemical identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess (ee), and key impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), this material should be stored under an inert gas (argon or nitrogen) in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Dark green to blue-green solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Chiral Purity (ee)	≥ 99% (by chiral HPLC or NMR)
Rhodium Content	Contact for details
Solvent Content (NMR)	≤ 5% (residual ethyl acetate)
Heavy Metals	≤ 50 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.