Description

2-Amino-7-(4-Chloro-Phenyl)-7,8-Dihydro-6H-Quinazolin-5-One is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for research into targeted therapies. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and CROs (Contract Research Organizations) engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially kinase inhibitors and other targeted small-molecule therapeutics.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic synthesis to construct complex quinazolinone-based molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of potential drugs.
• Biochemical Research: Employed in the study of enzyme inhibition and cellular signaling pathways due to its potential biological activity.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Amino-7-(4-Chloro-Phenyl)-7,8-Dihydro-6H-Quinazolin-5-One
CAS No.	299934-41-1
Molecular Formula	C14H12ClN3O
Molecular Weight	273.72 g/mol
Synonyms	2-Amino-7-(4-chlorophenyl)-7,8-dihydro-6H-quinazolin-5-one; 7-(4-Chlorophenyl)-2-amino-7,8-dihydro-5(6H)-quinazolinone; 299934-41-1; 2-Amino-7-(4-chlorophenyl)-5,6,7,8-tetrahydroquinazolin-5-one; 5(6H)-Quinazolinone, 7-(4-chlorophenyl)-2-amino-7,8-dihydro-; 2-Amino-7-(4-chlorophenyl)-5,6,7,8-tetrahydroquinazolin-5-one; 7-(4-Chlorophenyl)-2-amino-5,6,7,8-tetrahydroquinazolin-5-one
EINECS	Contact for details

Quality Control

Our 2-Amino-7-(4-Chloro-Phenyl)-7,8-Dihydro-6H-Quinazolin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.