Description

6-(Hexahydropyrrolo[1,2-A]Pyrazin-2(1H)-Yl)-1-(1-Naphthalenylsulfonyl)-1H-Indoledihydrochloride is a high-purity, non-peptidic small molecule compound of significant interest in advanced pharmaceutical research and development. This complex heterocyclic structure is valued for its potential as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical companies, biotechnology research firms, and academic institutions engaged in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and other disease areas.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates.
• Biochemical Research: Used as a reference standard or probe compound in pharmacological studies to investigate specific biological pathways and receptor interactions.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and structure-activity relationship (SAR) studies to optimize lead compounds.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and organic synthesis.
• Contract Research Organization (CRO) Services: Supplied to CROs conducting custom synthesis and preclinical development for client projects.
• API Development: Investigated for direct use as an active pharmaceutical ingredient in formulation development for clinical trials.

Basic Information

Product Name	6-(Hexahydropyrrolo[1,2-A]Pyrazin-2(1H)-Yl)-1-(1-Naphthalenylsulfonyl)-1H-Indoledihydrochloride
CAS No.	299433-10-6
Molecular Formula	C26H27Cl2N3O2S
Molecular Weight	516.48 g/mol
Synonyms	6-(Hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-1-(naphthalene-1-sulfonyl)-1H-indole dihydrochloride; 1-(1-Naphthalenesulfonyl)-6-(octahydropyrrolo[1,2-a]pyrazin-2-yl)-1H-indole dihydrochloride; 6-(Octahydropyrrolo[1,2-a]pyrazin-2-yl)-1-(naphthalen-1-ylsulfonyl)-1H-indole dihydrochloride; 299433-10-6; UNII-9H0G8V6J8I; 9H0G8V6J8I; 1H-Indole, 6-(hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-1-[(1-naphthalenyl)sulfonyl]-, dihydrochloride.
EINECS	Contact for details

Quality Control

Our 6-(Hexahydropyrrolo[1,2-A]Pyrazin-2(1H)-Yl)-1-(1-Naphthalenylsulfonyl)-1H-Indoledihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.