Description

Amino(3-Bromo-4-Fluorophenyl)Acetic Acid CAS NO 299164-16-2 is a high-purity, halogenated phenylglycine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both bromine and fluorine atoms, enabling precise modifications in target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, leveraging the halogenated aromatic system for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics & Bio-conjugation: The amino acid backbone makes it suitable for constructing peptidomimetic scaffolds and for bio-conjugation applications in chemical biology.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific electronic or structural properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Amino(3-Bromo-4-Fluorophenyl)Acetic Acid
CAS No.	299164-16-2
Molecular Formula	C8H7BrFNO2
Molecular Weight	248.05 g/mol
Synonyms	(3-Bromo-4-fluorophenyl)glycine; 2-Amino-2-(3-bromo-4-fluorophenyl)acetic acid; DL-3-Bromo-4-fluorophenylglycine; α-Amino-(3-bromo-4-fluorophenyl)acetic acid; 3-Bromo-4-fluoro-DL-phenylglycine; Amino(3-bromo-4-fluorophenyl)ethanoic acid; 2-(3-Bromo-4-fluorophenyl)glycine
EINECS	Contact for details

Quality Control

Every batch of Amino(3-Bromo-4-Fluorophenyl)Acetic Acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support cGMP (current Good Manufacturing Practice) compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.