Description

2-Phenanthrenol, 10-Ethoxy-4B,5,6,7,8,8A,9,10-Octahydro-4B,8,8-Trimethyl-1-(1-Methylethyl)-, (4Bs,8As,10R)- is a complex, high-purity octahydrophenanthrene derivative with a defined stereochemistry. This compound serves as a critical chiral intermediate or building block in advanced organic synthesis, where its unique polycyclic structure is essential for constructing complex molecular architectures. It is primarily required by pharmaceutical R&D and fine chemical manufacturers engaged in the development of novel active compounds, particularly in areas like medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in complex natural product synthesis.
• Advanced Organic Synthesis: Serves as a sophisticated building block for constructing complex polycyclic frameworks in academic and industrial research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new pharmacophores and bioactive molecules.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or liquid crystals due to its rigid, fused-ring system.
• Catalyst and Ligand Development: Can be utilized as a precursor for developing novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-Phenanthrenol, 10-Ethoxy-4B,5,6,7,8,8A,9,10-Octahydro-4B,8,8-Trimethyl-1-(1-Methylethyl)-, (4Bs,8As,10R)-
CAS No.	297179-10-3
Molecular Formula	C22H34O2
Molecular Weight	330.51 g/mol
Synonyms	(4Bs,8As,10R)-10-Ethoxy-4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)-2-phenanthrenol; 10-Ethoxy-4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(propan-2-yl)phenanthren-2-ol; (10R)-10-Ethoxy-4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-1-(1-methylethyl)phenanthren-2-ol; Octahydrophenanthrene derivative; CAS 297179-10-3
EINECS	Contact for details

Quality Control

Every batch of our high-purity chemical intermediates undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced R&D applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/GC), chiral purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.