Description

6-Iodo-3,4-Dihydro-1H-Quinolin-2-One is a versatile and synthetically valuable iodinated heterocyclic building block. This compound is of significant interest in advanced organic synthesis, particularly for the construction of complex nitrogen-containing scaffolds. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the development of novel active ingredients through cross-coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive quinolinone core.
• Material Science: Serves as a building block for organic electronic materials and photoactive compounds.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the iodine functional group for further derivatization.
• Academic & R&D: Used in university and corporate research laboratories for methodological studies and exploring new chemical spaces.
• Ligand and Catalyst Development: Potential use in creating novel ligands for metal complexes and catalysts.

Basic Information

Product Name	6-Iodo-3,4-Dihydro-1H-Quinolin-2-One
CAS No.	296759-29-0
Molecular Formula	C9H8INO
Molecular Weight	273.07 g/mol
Synonyms	6-Iodo-1,2,3,4-tetrahydroquinolin-2-one; 6-Iodo-3,4-dihydro-2(1H)-quinolinone; 6-Iodo-2-oxo-1,2,3,4-tetrahydroquinoline; 2-Quinolinone, 6-iodo-3,4-dihydro-; 6-Iodo-1,2,3,4-tetrahydroquinolin-2-one; 6-Iodo-2-tetrahydroquinolone
EINECS	Contact for details

Quality Control

Our 6-Iodo-3,4-Dihydro-1H-Quinolin-2-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is light-sensitive and easily oxidized; allow the sealed container to reach ambient temperature before opening to minimize moisture condensation and oxidation risk.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.