Description

6-Iodo-2-Piperazin-1-Yl-Quinoline is a high-value, functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a halogenated aromatic system and a piperazine moiety, makes it an essential intermediate for the development of novel pharmacologically active compounds. This chemical is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of targeted small molecule libraries and potential drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the development of targeted molecular probes.
• Chemical Biology: Employed in the design and synthesis of chemical tools for studying biological pathways and protein-ligand interactions.
• Agrochemical Development: Serves as an intermediate in the research and development of new active ingredients for crop protection.
• Material Science Research: Investigated as a potential monomer or functional additive for creating advanced polymers with specific electronic or optical properties.

Basic Information

Product Name	6-Iodo-2-Piperazin-1-Yl-Quinoline
CAS No.	296759-25-6
Molecular Formula	C₁₃H₁₄IN₃
Molecular Weight	355.18 g/mol
Synonyms	2-(Piperazin-1-yl)-6-iodoquinoline; 6-Iodo-2-(1-piperazinyl)quinoline; 6-Iodo-2-piperazinylquinoline; Quinoline, 6-iodo-2-(1-piperazinyl)-; 296759-25-6; 6-Iodo-2-piperazin-1-ylquinoline
EINECS	Contact for details

Quality Control

Our 6-Iodo-2-Piperazin-1-Yl-Quinoline is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation via spectroscopic methods (NMR, IR, MS), and residual solvent analysis. A detailed Certificate of Analysis (COA) is supplied with each batch, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.