Description

1-(5-Bromo-2-Methoxybenzenesulphonyl)Piperidine is a specialized sulfonamide derivative, a high-purity intermediate of significant value in advanced organic synthesis. Its unique molecular structure, featuring a brominated methoxybenzenesulfonyl group attached to a piperidine ring, makes it a critical building block for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its sulfonamide moiety for potential herbicidal or fungicidal activity.
• Chemical Biology & Proteomics: Acts as a versatile scaffold or linker molecule for the design of chemical probes, activity-based probes (ABPs), and affinity tags to study protein function and interactions.
• Material Science: Investigated as a monomer or additive for the synthesis of specialty polymers with tailored properties, such as high thermal stability or specific optical characteristics.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for methodological development, structure-activity relationship (SAR) studies, and library synthesis.

Basic Information

Product Name	1-(5-Bromo-2-Methoxybenzenesulphonyl)Piperidine
CAS No.	295360-83-7
Molecular Formula	C12H16BrNO3S
Molecular Weight	334.23 g/mol
Synonyms	1-[(5-Bromo-2-methoxyphenyl)sulfonyl]piperidine; 5-Bromo-2-methoxy-N-(piperidin-1-yl)benzenesulfonamide; Piperidine, 1-[(5-bromo-2-methoxyphenyl)sulfonyl]-; 1-(5-Bromo-2-methoxybenzenesulfonyl)piperidine; 295360-83-7; 5-Bromo-2-methoxybenzenesulfonylpiperidine; Benzenesulfonamide, 5-bromo-2-methoxy-N-(1-piperidinyl)-
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromo-2-Methoxybenzenesulphonyl)Piperidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.