Description

2-(2,3-Dimethyl-Phenyl)-1,3-Dioxo-2,3-Dihydro-1H-Isoindole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the isoindole-1,3-dione (phthalimide) class of compounds. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, where structural precision is paramount. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in developing and scaling up novel therapeutic agents and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Organic Synthesis Building Block: Utilized in research and development for constructing complex heterocyclic frameworks due to its reactive carboxylic acid and imide functionalities.
• Agrochemical Research: Employed in the development of new-generation pesticides and herbicides, where the isoindole core can contribute to biological activity.
• Material Science: Investigated for use in the synthesis of specialty polymers, dyes, and pigments that require thermally stable and structurally defined monomers.
• Academic & Contract Research: Used in university laboratories and CROs (Contract Research Organizations) for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	2-(2,3-Dimethyl-Phenyl)-1,3-Dioxo-2,3-Dihydro-1H-Isoindole-5-Carboxylic Acid
CAS No.	294667-08-6
Molecular Formula	C17H13NO4
Molecular Weight	295.29 g/mol
Synonyms	5-Carboxy-2-(2,3-dimethylphenyl)isoindole-1,3-dione; 2-(2,3-Dimethylphenyl)-1,3-dioxoisoindoline-5-carboxylic acid; 1H-Isoindole-5-carboxylic acid, 2,3-dihydro-2-(2,3-dimethylphenyl)-1,3-dioxo-; 294667-08-6; 2-(2,3-Dimethylphenyl)phthalimide-5-carboxylic acid; 5-Carboxy-2',3'-dimethylphthalimide; 2-(2,3-Xylyl)-1,3-dioxoisoindoline-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(2,3-Dimethyl-Phenyl)-1,3-Dioxo-2,3-Dihydro-1H-Isoindole-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The container should be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.