Description

4-(4-Bromo-Phenyl)-2,7,7-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydro-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its complex molecular architecture, featuring a brominated phenyl group and a fused quinoline-ester system, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Research: Used as a key building block for developing new generation pesticides, herbicides, and plant growth regulators, leveraging its bromine atom for further functionalization.
• Organic Synthesis & Catalysis: Acts as a sophisticated substrate or ligand precursor in catalytic reactions and asymmetric synthesis due to its sterically hindered and electron-rich structure.
• Material Science Precursor: Employed in the research and development of advanced organic materials, such as organic semiconductors, liquid crystals, or photoactive compounds.
• Academic & Contract Research: Essential for fundamental chemical research in universities and contract research organizations (CROs) exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	4-(4-Bromo-Phenyl)-2,7,7-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydro-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	292853-25-9
Molecular Formula	C21H24BrNO3
Molecular Weight	418.33 g/mol
Synonyms	Ethyl 4-(4-bromophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate; 4-(4-Bromophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylic Acid Ethyl Ester; 1,4,5,6,7,8-Hexahydro-4-(4-bromophenyl)-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 1,4,5,6,7,8-hexahydro-4-(4-bromophenyl)-2,7,7-trimethyl-5-oxo-, ethyl ester; CAS 292853-25-9
EINECS	Contact for details

Quality Control

Our production of 4-(4-Bromo-Phenyl)-2,7,7-Trimethyl-5-Oxo-1,4,5,6,7,8-Hexahydro-Quinoline-3-Carboxylic Acid Ethyl Ester adheres to stringent in-process controls and final batch analysis to ensure consistent high purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing results from advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Our quality management system supports compliance with cGMP and ISO standards for research-grade and development-scale materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.