Description

1,3,2-Dioxathiolane,4-(1-Methylethyl)-,2,2-Dioxide,(4R)-(9Ci) is a high-purity, chiral sulfite derivative of significant interest in advanced organic synthesis. This compound matters as a versatile chiral building block and reagent, enabling the stereoselective construction of complex molecules. It is primarily needed by research and development laboratories in the pharmaceutical and agrochemical sectors, as well as by fine chemical manufacturers specializing in enantiomerically pure intermediates. The product is supplied with a CAS number of 291780-07-9.

Application

• Chiral Auxiliary/Reagent: Used as a chiral sulfiting agent in asymmetric synthesis to introduce stereocenters.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides for enhanced efficacy.
• Ligand Precursor: Can be utilized in the preparation of chiral ligands for catalysis.
• Fine Chemical Production: Acts as a specialized intermediate for high-value flavors, fragrances, and other performance chemicals.
• Academic & Industrial Research: A valuable tool for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	1,3,2-Dioxathiolane,4-(1-Methylethyl)-,2,2-Dioxide,(4R)-(9Ci)
CAS No.	291780-07-9
Molecular Formula	C5H10O4S
Molecular Weight	166.20 g/mol
Synonyms	(4R)-4-Isopropyl-1,3,2-dioxathiolane 2,2-dioxide; (R)-4-Isopropyl-1,3,2-dioxathiolane-2,2-dioxide; (R)-(-)-4-Isopropyl-2-sulfolene; (R)-4-Isopropyl-2-sulfolene; (R)-4-Isopropyl-1,3,2-dioxathiolane-2,2-dioxide; (R)-4-(1-Methylethyl)-1,3,2-dioxathiolane 2,2-dioxide; Chiral isopropyl sulfite cyclic ester
EINECS	Contact for details

Quality Control

Our production of 1,3,2-Dioxathiolane,4-(1-Methylethyl)-,2,2-Dioxide,(4R)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Products undergo rigorous analytical testing, including chiral HPLC, NMR, and GC, to verify identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.