Description

Cyclopentanol, 2-[(3Ar,6Ar)-Hexahydrocyclopenta[B]Pyrrol-1(2H)-Yl]-, (1S,2S)- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its complex, fused bicyclic structure containing both cyclopentanol and pyrrolidine motifs makes it a valuable building block for constructing sophisticated molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets and complex alkaloid-like molecules.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule influences efficacy.
• Asymmetric Catalysis Ligand Precursor: Its structure can be modified to create novel chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry, including novel ring-forming reactions and stereocontrol strategies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	Cyclopentanol, 2-[(3Ar,6Ar)-Hexahydrocyclopenta[B]Pyrrol-1(2H)-Yl]-, (1S,2S)- (9Ci)
CAS No.	291541-67-8
Molecular Formula	C12H21NO
Molecular Weight	195.30 g/mol
Synonyms	(1S,2S)-2-[(3aR,6aR)-Hexahydrocyclopenta[b]pyrrol-1(2H)-yl]cyclopentanol; (1S,2S)-2-((3aR,6aR)-Octahydrocyclopenta[b]pyrrol-1-yl)cyclopentanol; (1S,2S)-rel-2-[(3aR,6aR)-Hexahydro-1H-cyclopenta[b]pyrrol-1-yl]cyclopentanol; 291541-67-8; Cyclopentanol, 2-(hexahydrocyclopenta[b]pyrrol-1(2H)-yl)-, (1S,2S)-rel-; A key chiral fused bicyclic amino alcohol intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality management protocols, ensuring batch-to-batch consistency and high chemical purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, chiral analysis, and NMR spectroscopy to confirm identity, purity, and enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications. We support compliance with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.